Article

A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth

2024-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Clade 2.3.4.4b H5N1 is causing an unprecedented outbreak in dairy cows in the United States. To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin (HA) from historical and recent 2.3.4.4b H5N1 viruses for binding to distinct glycans bearing terminal sialic acids. We found that H5 from A/Texas/37/2024, an isolate from the dairy cow outbreak, h...

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Literature Corpus work: 6e5a1812-5718-53d2-9285-3978d84ee112
DOI: 10.1101/2024.06.22.600211

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