Article

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential

2024-10-04

Abstract excerpt

<title>Abstract</title> <p>The recent 2.3.4.4b clade highly pathogenic avian influenza H5N1 infected diverse non-human mammalian species globally, gained mammal-to-mammal transmission potential and caused sporadic human infections. However, whether non-human mammals enable the human adaptation of 2.3.4.4b H5N1 to establish human infections is unclear. Gain-of-function research restrictions preclude assessing huma...

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Literature Corpus work: bcc16832-0c74-58a1-900c-b79ceea04b8d
DOI: 10.21203/rs.3.rs-5157982/v1

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