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Article

Integrating influenza antigenic dynamics with molecular evolution.

eLife - 1 Jan 2014

Bedford Trevor, Suchard Marc A, Lemey Philippe, Dudas Gytis, Gregory Victoria, Hay Alan J, McCauley John W, Russell Colin A, Smith Derek J, Rambaut Andrew

Abstract excerpt

Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains using the hemagglutination inhibition (HI) assay. Here, we extend previous approaches to antigenic cartography, and simultaneously characterize antigenic and...

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Source

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Identifiers

PMID: 24497547
DOI: 10.7554/eLife.01914
PMCID: PMC3909918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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