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Image-Based Profiling of Induced Trophoblast Stem Cells Identifies Signatures Associated with Sex, Schizophrenia Genomic Risk and Placental Stress

2025-12-25

Abstract excerpt

Schizophrenia (SCZ) is a neurodevelopmental disorder where both genetic and environmental risks converge during pregnancy. Recent studies have highlighted the importance of placental biology in influencing risk of developing SCZ. However, the pathways by which genetic risk factors for SCZ interact with environmental influences to alter placental development are poorly understood. Through image-based profiling usin...

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Literature Corpus work
ce69c8cf-b431-5dc3-a5c5-7975aeaf8544
DOI
10.64898/2025.12.23.695254
Open publication

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Image-Based Profiling of Induced Trophoblast Stem Cells Identifies Signatures Associated with Sex, Schizophrenia Genomic Risk and Placental StressDOI 10.64898/2025.12.23.695254
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