Article

Three-dimensional genome re-wiring in loci with Human Accelerated Regions

2022-10-05

Abstract excerpt

Human Accelerated Regions (HARs) are conserved genomic loci that evolved at an accelerated rate in the human lineage and may underlie human-specific traits. We generated HARs and chimpanzee accelerated regions with the largest alignment of mammalian genomes to date. To facilitate exploration of accelerated evolution in other lineages, we implemented an open-source Nextflow pipeline that runs on any computing platf...

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Literature Corpus work: 52fb5fa7-c025-5000-bcd4-02f80850ef7e
DOI: 10.1101/2022.10.04.510859

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