Article

Single-cell analysis reveals multicellular immune coordination and drug targets in driver-mutated NSCLC

2026-02-27

Abstract excerpt

<title>Abstract</title> <p>Non-small cell lung cancer (NSCLC) harboring driver mutations rely on specific oncogenic signaling pathways to promote tumor progression and remodel immune responses, yet the role of multicellular immune coordination within the tumor immune microenvironment (TIME) remains unclear. We performed single-cell transcriptomic profiling of ~ 200,000 cells from 45 untreated NSCLC patients with...

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Literature Corpus work: ce2a7799-5b62-5bad-8190-9138271aedc5
DOI: 10.21203/rs.3.rs-8727447/v1

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