Article

Single-Cell Transcriptomic Analyses of Tumor Ecosystems and Spatial Architectures in Human Small Cell Lung Cancer

2022-01-21

Abstract excerpt

<h4>ABSTRACT</h4> Small cell lung cancer (SCLC) is a highly heterogenous disease characterized by aggressive phenotypes and poor prognosis. In order to dissect the cellular components and their spatial distribution in SCLC ecosystems, here we performed single-cell RNA sequencing and spatial transcriptomics analyses of 12 resected human primary SCLCs. Our analysis revealed extensive heterogeneity of both tumor and...

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Literature Corpus work: 1ba39638-480a-5761-9d8d-e5cbec84eb87
DOI: 10.1101/2022.01.19.475968

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