Article

Multi-Omics reveals SPP1+ Malignant and CXCR4+ TAM crosstalk predicts immunotherapy response in lung adenocarcinoma cancer

2025-09-30

Abstract excerpt

<title>Abstract</title> <p>Background Lung adenocarcinoma cancer (LUAD), a common lung cancer subtype, is significantly influenced by the immune microenvironment. Immune checkpoint inhibitors have shown limited efficacy in Lung adenocarcinoma cancer due to the immunosuppressive tumor microenvironment (TME). Identifying predictive biomarkers for immunotherapy response remains an urgent clinical need. Methods Multi...

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Literature Corpus work: 3c8ccc3a-0533-5be4-9677-52ae51866b7f
DOI: 10.21203/rs.3.rs-7400400/v1

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