Article

BMI Interacts with the Genome to Regulate Gene Expression Globally, with Emphasis in the Brain and Gut

2024-11-28

Abstract excerpt

Genome-wide association studies identify common genomic variants associated with disease across a population. Individual environmental effects are often not included, despite evidence that environment mediates genomic regulation of higher order biology. Body mass index (BMI) is associated with complex disorders across clinical specialties, yet has not been modeled as a genomic environment. Here, we tested for expr...

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Literature Corpus work: ce227b20-9ac4-5fca-a387-40a42970efb5
DOI: 10.1101/2024.11.26.24317923

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