Article

Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities

2018-06-06

Abstract excerpt

Clinical studies of non-communicable diseases identify multimorbidities that reflect our relatively limited fixed metabolic capacity. Despite the fact that we have ∼24000 genes, we do not understand the genetic pathways that contribute to the development of multimorbid non-communicable disease. We created a “multimorbidity atlas” of traits based on pleiotropy of spatially regulated genes using convex biclustering....

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Literature Corpus work: d9e394ee-17c9-58d6-9a84-322117a7e27c
DOI: 10.1101/340216

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