Article

PIWI-piRNA pathway-mediated transposable element repression in <i>Hydra</i> somatic stem cells

2019-08-10

Abstract excerpt

Transposable elements (TEs) can damage genomes, thus organisms employ a variety of mechanisms to repress TE expression. However, these mechanisms often fail over time leading to de-repression of TEs in aging tissues. The PIWI-piRNA pathway is a small RNA pathway that represses TE expression in the germline of animals. Here we explore the function of the pathway in the epithelial stem cells of Hydra , a long-lived...

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Literature Corpus work: 84886fd0-eeba-5f4a-ab99-282c3104d489
DOI: 10.1101/731695

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