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Deep Proteomic Profiling of Human Stem Cell-Derived Microglia: Insights Into Inflammatory and Alcohol-Induced Reactivity

2025-11-17

Abstract excerpt

<title>Abstract</title> <p>Alcohol use disorder (AUD) is associated with significant neuroimmune dysregulation, with microglia emerging as a potential pathological driver of neurotoxicity. However, the molecular landscape driving this alcohol-induced reactivity has yet to be uncovered, especially in the context of human microglia. Here, we comprehensively characterized global-scale molecular changes of human stem...

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Literature Corpus work
cde2c39f-f258-516e-ba5c-524772bc87f4
DOI
10.21203/rs.3.rs-7983368/v1
Open publication

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Deep Proteomic Profiling of Human Stem Cell-Derived Microglia: Insights Into Inflammatory and Alcohol-Induced ReactivityDOI 10.21203/rs.3.rs-7983368/v1
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