Article
Microglia Phenotypes Following the Induction of Alcohol Dependence in Adolescent Rats.
Alcoholism, clinical and experimental research - 1 Jan 2021
Peng Hui, Nixon Kimberly
Abstract excerpt
BACKGROUND: Activation of the innate immune system may play a role in the development of alcohol use disorders (AUDs), which often originate with adolescent alcohol abuse. A key player in the innate immune system is microglia, the activation of which occurs along a spectrum from proinflammatory, or M1-like, to anti-inflammatory, or M2-like, phenotypes. METHODS: Adolescent, male rats were gavaged with ethanol...
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