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Article

Increased expression of M1 and M2 phenotypic markers in isolated microglia after four-day binge alcohol exposure in male rats.

Alcohol (Fayetteville, N.Y.) - 1 Aug 2017

Peng Hui, Geil Nickell Chelsea R, Chen Kevin Y, McClain Justin A, Nixon Kimberly

Abstract excerpt

Microglia activation and neuroinflammation are common features of neurodegenerative conditions, including alcohol use disorders (AUDs). When activated, microglia span a continuum of diverse phenotypes ranging from classically activated, pro-inflammatory (M1) microglia/macrophages to alternatively activated, growth-promoting (M2) microglia/macrophages. Identifying microglia phenotypes is critical for understanding...

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Identifiers

PMID: 28755749
DOI: 10.1016/j.alcohol.2017.02.175
PMCID: PMC5695703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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