Article

Transcriptional, epigenetic, and functional reprogramming of blood monocytes in non-human primates following chronic alcohol drinking

2021-05-13

Abstract excerpt

<h4>ABSTRACT</h4> Chronic heavy drinking (CHD) of alcohol is a known risk factor for increased susceptibility to bacterial and viral infection as well as impaired wound healing. Evidence suggests that these defects are mediated by a dysregulated inflammatory response originating from myeloid cells, notably monocytes and macrophages, but the mechanisms remain poorly understood. Our ability to study CHD is impacted...

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Literature Corpus work: 11399295-1e46-5393-b935-dbc9ad79e3e1
DOI: 10.1101/2021.05.12.443856

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