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Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues.

Molecular cell - 16 Jan 2020

Liu Jun'e, Li Kai, Cai Jiabin, Zhang Mingchang, Zhang Xiaoting, Xiong Xushen, Meng Haowei, Xu Xizhan, Huang Zhibin, Peng Jinying, Fan Jia, Yi Chengqi

Abstract excerpt

N6-methyladenosine (m6A), the most abundant internal mRNA modification, and N6,2'-O-dimethyladenosine (m6Am), found at the first-transcribed nucleotide, are two reversible epitranscriptomic marks. However, the profiles and distribution patterns of m6A and m6Am across human and mouse tissues are poorly characterized. Here, we report the m6A and m6Am methylome through profiling of 43 human and 16 mouse tissues and...

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PMID: 31676230
DOI: 10.1016/j.molcel.2019.09.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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