Article

CD8 T cell hyperfunction and reduced tumour control in models of advanced liver fibrosis

2023-09-22

Abstract excerpt

Immune dysfunction, both depression and hyperactivation, in liver disease contributes to significant morbidities and mortalities, depending on liver damage severity and etiology. The underlying causes of immune dysfunction in advanced liver disease, whether pathogen or host-mediated, remain unclear. We reported lasting generalized CD8 + T cell hyperfunction in individuals with advanced liver fibrosis in chronic H...

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Literature Corpus work: cd256f04-a7a1-511a-9180-2efe6e49cd06
DOI: 10.1101/2023.09.20.557752

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