Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The T Cell Receptor Immune Repertoire Protects the Liver From Reconsitution

18 Dec 2020

Abstract excerpt

Aberrant immune cell infiltrates and microcircumstances represent characteristic features of liver fibrosis. In this study, we profiled the transcriptomes of intrahepatic CD45 + immune cells, from mice, using single-cell RNA sequencing (scRNA-seq) technology to understand the landscape of intrahepatic immune cells during the pathogenesis of fibrosis. Analysis of approximately 10,000 single-cell transcriptomes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Disease Diagnosis and Treatment
Share to Liver physiology and pathology
Share to Organ Transplantation Techniques and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33391261
DOI: 10.3389/fimmu.2020.584979

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The T Cell Receptor Immune Repertoire Protects the Liver From ReconsitutionPMID 33391261Read ↗

Single‐cell RNA sequencing reveals the heterogeneity and intercellular communication of hepatic stellate cells and macrophages during liver fibrosisSemantic proximity Read ↗

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosisSemantic proximity Read ↗

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomicsSemantic proximity Read ↗

Single cell RNA-sequencing delineates CD8 + tissue resident memory T cells maintaining rejection in liver transplantationSemantic proximity Read ↗

Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitisSemantic proximity Read ↗

Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesisSemantic proximity Read ↗

CD4 <sup>+</sup> T cells promote fibrosis during metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

An integrated single-cell atlas of checkpoint inhibitor-induced liver injury links shared liver-tumour CD8+ T cell clones to cytotoxicity and macrophage crosstalksSemantic proximity Read ↗

Decoding liver fibrogenesis with single-cell technologiesSemantic proximity Read ↗

Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversitySemantic proximity Read ↗

Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liverSemantic proximity Read ↗

Decoding Single-cell Landscape and Intercellular Crosstalk in the Transplanted LiverSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.