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Article

Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.

Gastroenterology - 1 Nov 2017

Bolte Fabian J, O'Keefe Ashley C, Webb Lauren M, Serti Elisavet, Rivera Elenita, Liang T Jake, Ghany Marc, Rehermann Barbara

Abstract excerpt

BACKGROUND & AIMS: Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV)...

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Identifiers

PMID: 28780074
DOI: 10.1053/j.gastro.2017.07.043
PMCID: PMC5669813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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