Article

Response of human liver tissue to innate immune stimuli

2020-12-24

Abstract excerpt

Precision-cut human liver slice cultures (PCLS) has become an important alternative immunological platform in preclinical testing. To further evaluate the capacity of PCLS, we investigated the innate immune response to TLR3 agonist (poly-I:C) and TLR4 agonist (LPS) with the normal and pathological liver tissue. Pathological liver tissue was obtained from patients with active chronic HCV infection, and patients wit...

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Literature Corpus work: 265c415a-f320-5d92-9c62-5e417875d167
DOI: 10.1101/2020.12.22.20248755

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