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Macrophage-derived GPNMB Trapped by Fibrotic Extracellular Matrix Promotes Pulmonary Fibrosis

2022-03-24

Abstract excerpt

<title>Abstract</title> <p>Pulmonary fibrosis (PF) is a form of progressive lung disease characterized by chronic inflammation and excessive extracellular matrix (ECM) deposition. The pulmonary ECM undergoes profound changes during fibrosis. However, the protein changes that occur in fibrotic ECM during silica-induced progressive PF and their contribution to fibrosis progression are unclear. Here, we established...

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Literature Corpus work
cca14395-13c2-59df-8756-3b82c416f5c0
DOI
10.21203/rs.3.rs-1360030/v1
Open publication

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Macrophage-derived GPNMB Trapped by Fibrotic Extracellular Matrix Promotes Pulmonary FibrosisDOI 10.21203/rs.3.rs-1360030/v1
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