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Article

Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis

19 Jul 2023

Abstract excerpt

Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools. Epithelial mesenchymal transition plays an important role in several diseases; however, data on the specific mechanisms in silicosis models are scarce. We elucidated the pathogenesis of pulmonary fibrosis via single-cell transcriptome...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37468937
DOI: 10.1186/s12989-023-00543-9

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