Article

Elucidating the Role of Immune Cell Dysregulation in Atypical Hemolytic Uremic Syndrome: A Comprehensive Single-Cell Sequencing Analysis

2023-05-16

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury, necessitating differentiation from other thrombotic microangiopathy disorders. Definitive biomarkers for disease diagnosis and activity are currently lacking, and identifying molecular markers is essential. We conducted single-cell sequencin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cc7bed49-4f46-5220-9d58-3bc66790c584
DOI: 10.20944/preprints202305.1104.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elucidating the Role of Immune Cell Dysregulation in Atypical Hemolytic Uremic Syndrome: A Comprehensive Single-Cell Sequencing AnalysisDOI 10.20944/preprints202305.1104.v1Read

The transcriptomic landscape of normal and ineffective erythropoiesis at single cell resolutionSemantic proximity Read

Single-cell transcriptomic analysis identifies an immune erythroid in paroxysmal nocturnal hemoglobinuriaSemantic proximity Read

A review of genetic and epigenetic biomarkers involved in the occurrence of atypical hemolytic uremic syndrome and its therapeutic strategies.Semantic proximity Read

Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome.Semantic proximity Read

Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension.Semantic proximity Read

The transcriptomic landscape of normal and ineffective erythropoiesis at single-cell resolutionSemantic proximity Read

A multiomic analysis of Waldenström macroglobulinemia defines distinct disease subtypesSemantic proximity Read

Single-cell sequencing analysis of peripheral blood in patients with moyamoya diseaseSemantic proximity Read

Single cells and TRUST4 reveal immunological features of the HFRS transcriptomeSemantic proximity Read

‘Trans-differentiation of neutrophils from plasmablast’ is an artefact caused by over-reliance on machine algorithms in single cell RNA sequencing analysis: Lesson learnt and steps aheadSemantic proximity Read

Consensus regarding diagnosis and management of atypical hemolytic uremic syndromeSemantic proximity Read

Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomicsSemantic proximity Read