Article

Single-cell transcriptomic analysis identifies an immune erythroid in paroxysmal nocturnal hemoglobinuria

2025-10-08

Abstract excerpt

<title>Abstract</title> <p>Introduction: PNH is complement mediated intravascular hemolysis, the mechanism of intrinsic immune-like transcriptional programs within erythroid remains unclear. Methods Bone marrow samples were collected from patients with PNH and healthy controls. CD59-/+ cells were isolated for single-cell sequencing analysis, based on differential gene markers, erythroid cells were classified into...

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Literature Corpus work: a3b5dcca-9de9-50e9-ab13-738cfe71f673
DOI: 10.21203/rs.3.rs-7363120/v1

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