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Article

Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics

24 Aug 2023

Abstract excerpt

Abstract Background Myasthenia gravis (MG) is the most prevalent autoimmune disorder affecting the neuromuscular junction. A rapid deterioration in respiratory muscle can lead to a myasthenic crisis (MC), which represents a life-threatening condition with high mortality in MG. Multiple CD4 + T subsets and hypercytokinemia have been identified in the peripheral pro-inflammatory milieu during the crisis. However,...

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Share to Chemokine receptors and signaling
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PMID: 37620910
DOI: 10.1186/s12967-023-04421-y

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