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Article

A review of genetic and epigenetic biomarkers involved in the occurrence of atypical hemolytic uremic syndrome and its therapeutic strategies.

Molecular biology reports - 14 May 2026

Tohidi Mohamadreza, Mohammadi Mahan

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare, chronic, and life-threatening thrombotic microangiopathy (TMA). The disease is most frequently linked to genetic or acquired dysregulation of the alternative complement pathway and affects both children and adults. The paucity of a gold standard for diagnostic testing and the variety of clinical manifestations are the primary reasons for the challenge in...

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Identifiers

PMID: 42133203
DOI: 10.1007/s11033-026-11912-w

Genes

C5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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