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Article

Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension.

Journal of thrombosis and haemostasis : JTH - 1 May 2025

Zhang Rui, Zhang Yunlong, Li Huiting, Zhang Jing, Feng Qiao, Lei Yitong, Liu Sihan, Zhao Qinhua, He Jing, Luo Cijun, Qiu Hongling, Zhang Jianfeng, Gong Sugang, Wang Lan

Abstract excerpt

BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) presents challenges due to its complex pathobiology. Although numerous studies have reported heterogeneous cell types by single-cell RNA sequencing, the atlas and characteristics of plasma cells remain poorly understood. OBJECTIVES: To identify the altered phenotype and differentiation patterns of plasma cells in CTEPH. METHODS: We performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39965671
DOI: 10.1016/j.jtha.2025.02.010

Genes

AHNAK
HSPA1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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