Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains

doi:10.1136/gut.41.4.442

Article

Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains

1 Oct 1997

Abstract excerpt

BACKGROUND: Helicobacter pylori strains possessing the cagA gene are thought to induce interleukin 8 (IL-8) in gastric mucosa. However, it is still unclear whether a relation exists between the cagA gene and the expression patterns of cytokines other than IL-8. AIMS: To investigate the relation between the cagA gene and the production of various cytokine proteins using an enzyme linked immunosorbent assay...

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Induction of various cytokines and development of severe mucosal inflammation by <i>cagA</i> gene positive <i>Helicobacter pylori</i> strains

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