Article
Proteins Encoded by the cag Pathogenicity Island of Helicobacter pylori Are Required for NF-κB Activation
1 May 1998
Abstract excerpt
Helicobacter pylori is the etiological agent in the development of chronic gastritis, duodenal ulceration, and gastric adenocarcinoma. The difference in virulence between individual strains is reflected in their ability to induce interleukin-8 (IL-8) secretion from gastric epithelial cells. It has been shown that virulence is associated with the presence of a bacterial gene cluster (a pathogenicity island). We...
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