Article

DNA methylation in the APOE gene: its link with Alzheimer’s and cardiovascular health

2019-10-21

Abstract excerpt

Genetic variation in the apolipoprotein E ( APOE ) gene is associated with Alzheimer’s disease (AD) and risk factors for cardiovascular disease (CVD). DNA methylation at APOE has been linked to altered cognition and AD. It is unclear if epigenetic marks could be used for predicting future disease. We assessed blood-based DNA methylation at 13 CpGs in the APOE gene in 5828 participants from the Generation Scotla...

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Literature Corpus work: cc07296a-0702-5b07-b23b-f07dbdad222e
DOI: 10.1101/811224

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