Article

Deep phenotypic profiling uncovers cryptic effects of antifilarial drugs

2026-02-13

Abstract excerpt

The anthelmintics ivermectin, albendazole, and diethylcarbamazine are the backbone of mass drug administration (MDA) campaigns targeting human filariasis, yet their direct effects on parasites are still not fully defined or understood. The clinical effects of these drugs are stage dependent, resulting in effective clearance of circulating microfilariae but only limited activity against adult worms, a pattern that...

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Literature Corpus work: cbfe46cf-0f54-5db3-9f2a-2aff3e657a7e
DOI: 10.64898/2026.02.12.705610

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