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The Effects of Ivermectin on Brugia malayi Females In Vitro: A Transcriptomic Approach

16 Aug 2016

Abstract excerpt

BACKGROUND: Lymphatic filariasis and onchocerciasis are disabling and disfiguring neglected tropical diseases of major importance in developing countries. Ivermectin is the drug of choice for mass drug administration programs for the control of onchocerciasis and lymphatic filariasis in areas where the diseases are co-endemic. Although ivermectin paralyzes somatic and pharyngeal muscles in many nematodes, these...

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PMID: 27529747
DOI: 10.1371/journal.pntd.0004929

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