Article

Ivermectin inhibits extracellular vesicle secretion from parasitic nematodes

2020-07-21

Abstract excerpt

Lymphatic filariasis (LF) is a disease caused by parasitic filarial nematodes that is endemic in 49 countries and affects or threatens over 890 million people. Strategies to control LF rely heavily on mass administration of anthelmintic drugs including ivermectin (IVM), a macrocyclic lactone drug considered an Essential Medicine by the WHO. However, despite its widespread use the therapeutic mode of action of IVM...

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Literature Corpus work: 1cab200f-76d3-58b4-8d55-a59286b19201
DOI: 10.1101/2020.07.20.212290

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