Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiling extracellular vesicle release by the filarial nematode Brugia malayi reveals sex-specific differences in cargo and a sensitivity to ivermectin

16 Apr 2018

Abstract excerpt

The filarial nematode Brugia malayi is an etiological agent of Lymphatic Filariasis. The capability of B. malayi and other parasitic nematodes to modulate host biology is recognized but the mechanisms by which such manipulation occurs are obscure. An emerging paradigm is the release of parasite-derived extracellular vesicles (EV) containing bioactive proteins and small RNA species that allow secretion of parasite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Parasite Biology and Host Interactions
Share to Parasitic Diseases Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29659599
DOI: 10.1371/journal.pntd.0006438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiling extracellular vesicle release by the filarial nematode Brugia malayi reveals sex-specific differences in cargo and a sensitivity to ivermectinPMID 29659599Read ↗

Extracellular vesicles secreted by <i>Brugia malayi</i> microfilariae modulate the melanization pathway in the mosquito hostSemantic proximity Read ↗

Extracellular vesicles secreted by Brugia malayi microfilariae modulate the melanization pathway in the mosquito hostSemantic proximity Read ↗

Ivermectin inhibits extracellular vesicle secretion from parasitic nematodesSemantic proximity Read ↗

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolutionSemantic proximity Read ↗

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolutionSemantic proximity Read ↗

Secreted filarial nematode galectins modulate host immune cellsSemantic proximity Read ↗

Stage-specific proteomic expression patterns of the human filarial parasite <i>Brugia malayi</i> and its endosymbiont <i>Wolbachia</i>Semantic proximity Read ↗

Brugia malayi Excreted/Secreted Proteins at the Host/Parasite Interface: Stage- and Gender-Specific Proteomic ProfilingSemantic proximity Read ↗

Deep phenotypic profiling uncovers cryptic effects of antifilarial drugsSemantic proximity Read ↗

Insights into the L3 to L4 developmental program through proteomicsSemantic proximity Read ↗

Defining Brugia malayi and Wolbachia symbiosis by stage-specific dual RNA-seqSemantic proximity Read ↗

Comparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.