Article

Development and validation of a population pharmacokinetic model to guide perioperative tacrolimus dosing after lung transplantation

2023-06-27

Abstract excerpt

<h4>Background</h4> Tacrolimus therapy is standard of care for immunosuppression after lung transplantation. However, tacrolimus exposure variability during the early postoperative period may contribute to poor outcomes in this population. Few studies have examined tacrolimus pharmacokinetics (PK) during this high-risk time period. <h4>Methods</h4> We conducted a retrospective pharmacokinetic study in lung transpl...

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Literature Corpus work: cbaf616b-38bf-504e-b66b-066a056c9e02
DOI: 10.1101/2023.06.26.23291248

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