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Article

Population Pharmacokinetic Models of Tacrolimus in Adult Transplant Recipients: A Systematic Review.

Clinical pharmacokinetics - 1 Nov 2020

Kirubakaran Ranita, Stocker Sophie L, Hennig Stefanie, Day Richard O, Carland Jane E

Abstract excerpt

BACKGROUND AND OBJECTIVES: Numerous population pharmacokinetic (PK) models of tacrolimus in adult transplant recipients have been published to characterize tacrolimus PK and facilitate dose individualization. This study aimed to (1) investigate clinical determinants influencing tacrolimus PK, and (2) identify areas requiring additional research to facilitate the use of population PK models to guide tacrolimus...

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Identifiers

PMID: 32783100
DOI: 10.1007/s40262-020-00922-x

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