Article
Population pharmacokinetic analyses of tacrolimus in non-transplant patients: a systematic review.
European journal of clinical pharmacology - 1 Jul 2023
Wang Cheng-Bin, Zhang Yu-Jia, Zhao Ming-Ming, Zhao Li-Mei
Abstract excerpt
BACKGROUND AND OBJECTIVES: Tacrolimus (TAC) has been increasingly used in patients with non-transplant settings. Because of its large between-subject variability, several population pharmacokinetic (PPK) studies have been performed to facilitate individualized therapy. This review summarized published PPK models of TAC in non-transplant patients, aiming to clarify factors affecting PKs of TAC and identify the...
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