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Population pharmacokinetic characteristics of tacrolimus in Chinese lung transplant recipients and optimisation of dosing regimen

2022-07-18

Abstract excerpt

<h4>Purpose: </h4> To establish a population pharmacokinetic model and optimise tacrolimus dosing regimens in Chinese Han lung transplant recipients. <h4>Methods: </h4> A total of 780 tacrolimus trough concentrations and clinical data of 127 adult lung transplant recipients were collected. Population pharmacokinetic analysis was performed using a nonlinear mixed effects model. A Monte Carlo simulation was conducte...

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Literature Corpus work
2d8ac1ea-0a1c-51d3-b674-d468432f8720
DOI
10.21203/rs.3.rs-1829496/v1
Open publication

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Population pharmacokinetic characteristics of tacrolimus in Chinese lung transplant recipients and optimisation of dosing regimenDOI 10.21203/rs.3.rs-1829496/v1
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