Article
Population pharmacokinetic-pharmacogenetic model of tacrolimus in the early period after kidney transplantation.
Basic & clinical pharmacology & toxicology - 1 May 2014
Han Nayoung, Ha Soojung, Yun Hwi-yeol, Kim Myeong Gyu, Min Sang-Il, Ha Jongwon, Lee Jangik Ike, Oh Jung Mi, Kim In-Wha
Abstract excerpt
As tacrolimus has a rather narrow therapeutic range and high individual variability in its pharmacokinetics, it is important to determine the cause of the variation in tacrolimus pharmacokinetics. The purpose of this study was to establish a population pharmacokinetic-pharmacogenetic model of tac...
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