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Population pharmacokinetic characteristics of tacrolimus in Chinese Han lung transplant recipients and optimisation of dosing regimen

2021-10-26

Abstract excerpt

<h4>Aim: </h4> To establish a population pharmacokinetic model and optimise tacrolimus dosing regimens in Chinese Han lung transplant recipients. <h4>Methods:</h4> Tacrolimus trough concentrations and clinical data of 70 adult lung transplant recipients were collected. Population pharmacokinetic analysis was performed using a nonlinear mixed effects model. A Monte Carlo simulation was conducted to determine the op...

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Literature Corpus work
6ad3f84b-93f1-5d5c-b6ee-6b8187d02f5e
DOI
10.22541/au.163522685.51818576/v1
Open publication

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Population pharmacokinetic characteristics of tacrolimus in Chinese Han lung transplant recipients and optimisation of dosing regimenDOI 10.22541/au.163522685.51818576/v1
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