Article

Three-dimensional genome structure and chromatin accessibility reorganization during <i>in vivo</i> induction of human T cell tolerance

2020-03-12

Abstract excerpt

<h4>SUMMARY</h4> Achieving T cell tolerance is a pivotal goal for the field of transplantation and autoimmune diseases. Here, we characterized the gene expression profiles, 3D genome architecture and chromatin accessibility in human steady-state and tolerant T cells, which had been induced in healthy donors by granulocyte-colony-stimulating factor in vivo . We provided the first high-resolution 3D genomic landsc...

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Literature Corpus work: cb321738-ae70-5531-895a-44025870d9d3
DOI: 10.1101/2020.03.11.988253

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