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Article

Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation.

Cell reports - 30 May 2017

Tripathi Subhash K, Chen Zhi, Larjo Antti, Kanduri Kartiek, Nousiainen Kari, Äijo Tarmo, Ricaño-Ponce Isis, Hrdlickova Barbara, Tuomela Soile, Laajala Essi, Salo Verna, Kumar Vinod, Wijmenga Cisca, Lähdesmäki Harri, Lahesmaa Riitta

Abstract excerpt

The development of therapeutic strategies to combat immune-associated diseases requires the molecular mechanisms of human Th17 cell differentiation to be fully identified and understood. To investigate transcriptional control of Th17 cell differentiation, we used primary human CD4+ T cells in small interfering RNA (siRNA)-mediated gene silencing and chromatin immunoprecipitation followed by massive parallel...

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Source

Identifiers

PMID: 28564606
DOI: 10.1016/j.celrep.2017.05.013

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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