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Biochemical identification of a nuclear coactivator protein required for AtrR-dependent gene regulation in <i>Aspergillus fumigatus</i>

2022-09-28

Abstract excerpt

Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus . A central player in azole resistance is the Zn 2 Cys 6 zinc cluster-containing transcription factor AtrR. This factor stimulates expression of the both the cyp51A gene encoding the azole drug target enzyme as well as an ATP-binding cassette transporter-encoding gene called abc...

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Literature Corpus work
ca0f9e35-ada3-5379-99e1-f7b92b8c7854
DOI
10.1101/2022.09.26.509624
Open publication

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Biochemical identification of a nuclear coactivator protein required for AtrR-dependent gene regulation in <i>Aspergillus fumigatus</i>DOI 10.1101/2022.09.26.509624
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