Article
Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.
BMC microbiology - 15 Jan 2010
Soriani Frederico M, Malavazi Iran, Savoldi Marcela, Espeso Eduardo, Dinamarco Taísa M, Bernardes Luciano A S, Ferreira Márcia E S, Goldman Maria Helena S, Goldman Gustavo H
Abstract excerpt
BACKGROUND: Calcineurin, a serine/threonine-specific protein phosphatase, plays an important role in the control of cell morphology and virulence in fungi. Calcineurin regulates localization and activity of a transcription factor called CRZ1. Recently, we characterize Aspergillus fumigatus CRZ1 homologue, AfCrzA. Here, we investigate which pathways are influenced by A. fumigatus AfCrzA during a short pulse of...
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