Article

A long non-coding RNA regulates in vitro and in vivo triazole antifungal susceptibility in <i>Aspergillus fumigatus</i>

2025-10-16

Abstract excerpt

Azole-resistant Aspergillus infections are a source of increasing concern with limited alternative therapeutic options. However, as most infections are still caused by azole-susceptible Aspergillus strains, there is a need to better understand fungal responses to azole antifungals. To this end, we discover that a long non-coding RNA, afu-182, is a major regulator of cyp51- independent sub-MIC azole response. W...

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Literature Corpus work: 6e5a333c-926f-5c23-b089-8ffa8350331f
DOI: 10.1101/2025.10.16.682787

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