Article

Interplay between canonical Wnt signaling and α5β1 integrins modulates mechanoresponse in human articular cartilage

2026-05-21

Abstract excerpt

<h4>Objectives</h4> Mechanical cues are essential for maintaining cartilage function, yet how they integrate with molecular pathways dysregulated in osteoarthritis (OA) remains poorly defined in human tissue. Canonical Wnt signalling influences cartilage biology and cell–matrix interactions, but its role in integrin-dependent mechanoregulation in human cartilage is not fully understood. This study aimed to determ...

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Literature Corpus work: c9d49434-5cb4-5ce0-82b3-e6cd615cd050
DOI: 10.64898/2026.05.20.726448

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