Article

Cell Biology of Knee Joint Injuries: Early Mechanical Loading Perspective

2024-09-09

Abstract excerpt

Knee joint injuries, including those affecting the anterior cruciate ligament (ACL), meniscus, and cartilage, present complex challenges in sports medicine and orthopedics due to the intricate cellular and molecular mechanisms involved in tissue damage and repair. Understanding the molecular biology underpinning these processes is crucial for developing effective therapeutic and rehabilitation strategies. This sys...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5c45da2e-d009-5871-803c-dabdc991e5dd
DOI: 10.20944/preprints202408.0190.v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cell Biology of Knee Joint Injuries: Early Mechanical Loading PerspectiveDOI 10.20944/preprints202408.0190.v3Read

Knee Joint Response to Mechanical Loading: Bounding Mechanotransduction with RehabilitationSemantic proximity Read

Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genesSemantic proximity Read

Hippo Signaling Modulates the Inflammatory Response of Chondrocytes to Mechanical Compressive LoadingSemantic proximity Read

Mechanical loading rescues mechanoresponsiveness in a human osteoarthritis explant model despite Wnt activationSemantic proximity Read

Mechanobiology in cellular, molecular, and tissue adaptationSemantic proximity Read

Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward mechanismSemantic proximity Read

Effect of Micro-strain Stress on in Vitro Proliferation and Functional Expression of Human Osteoarthritic ChondrocytesSemantic proximity Read

Molecular Aspects of Cartilage Microfracturation: Rehabilitation Insights.Semantic proximity Read

Feeling Things Out: Bidirectional Signaling of the Cell–ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and DifferentiationSemantic proximity Read

Molecular Mechanism Study of Medial Open-Wedge High Tibial Osteotomy in Treating Medial Compartment Osteoarthritis of the Knee by Improving the Intra-Articular EnvironmentSemantic proximity Read

Low-Magnitude Mechanical Loading Modulates Age-Related Changes in the Temporomandibular Joint via TRPV4Semantic proximity Read

The Myofibroblast Fate of Therapeutic Mesenchymal Stromal Cells: Regeneration, Repair, or Despair?Semantic proximity Read