Article
Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt‐16 expression and signaling after injury and in osteoarthritis
25 Apr 2008
Abstract excerpt
OBJECTIVE: To characterize the molecular response of adult human articular cartilage to acute mechanical injury. METHODS: An established ex vivo model was used to compare gene expression of adult human articular cartilage explants 24 hours after mechanical injury with that of uninjured controls by microarray analysis of gene expression. Confirmation for selected genes was obtained by real-time polymerase chain...
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