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Article

Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury

7 Aug 2006

Abstract excerpt

Acute full thickness joint surface defects can undergo repair, which involves tissue patterning and endochondral bone formation. Molecular signals regulating this process may contribute to the repair outcome, chronic evolution and, eventually, the onset of osteoarthritis. We tested the hypothesis that mechanical injury modulates morphogenetic pathways in adult human articular cartilage explants. Adjacent...

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PMID: 16893455
DOI: 10.1186/ar2029

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