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Iso-Seq enables discovery of novel isoform variants in human retina at single cell resolution

2024-08-09

Abstract excerpt

Recent single cell transcriptomic profiling of the human retina provided important insights into the genetic signals in heterogeneous retinal cell populations that enable vision. However, conventional single cell RNAseq with 3’ short-read sequencing is not suitable to identify isoform variants. Here we utilized Iso-Seq with full-length sequencing to profile the human retina at single cell resolution for isoform di...

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Literature Corpus work
2c942ff6-626e-53c8-b424-2339ce0e92a6
DOI
10.1101/2024.08.08.607267
Open publication

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Iso-Seq enables discovery of novel isoform variants in human retina at single cell resolutionDOI 10.1101/2024.08.08.607267
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